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VOLUME 5 , ISSUE 2 ( July-December, 2017 ) > List of Articles

ORIGINAL RESEARCH ARTICLE

A study of red cell distribution width in hypertensive individuals

Deepa Gunasekaran, Viji Devanand, Sasirekha G, Celine D, Umayal CC, Niveditha Pari

Keywords : inflammation, hypertension, red cell distribution width

Citation Information : Gunasekaran D, Devanand V, G S, D C, CC U, Pari N. A study of red cell distribution width in hypertensive individuals. 2017; 5 (2):16-20.

DOI: 10.5005/NJP-11056-05_02_04

License: CC BY-NC 4.0

Published Online: 01-12-2017

Copyright Statement:  Copyright © 2017; NA


Abstract

Background: Hypertension is a global health issue and is a multifactorial disorder caused by various environmental, physiological and genetic factors. Inflammation plays a major role in the development of hypertension. Research has shown that Red cell distribution width (RDW) has significant association with cardiovascular and thrombotic disorders, and cardiac mortality in patients with coronary artery disease, acute and chronic heart failure, and stroke. Aim:: To determine RDW in hypertensive individuals and to compare this with that of normal individuals. Materials and methods: Thirty hypertensive individuals of both genders in the age group of 30 - 45 years were chosen from Department of General Medicine, Stanley Medical College and Hospital, Chennai. Thirty age- and gender-matched healthy controls were selected. Under strict aseptic conditions, venous blood sample was collected for measuring RDW. Results: The data obtained were analyzed using SPSS software version 20. From this study we found that RDW was significantly higher (p =0.000) in hypertensive individuals (15.25± 2.06) compared to controls (13.08 ± 0.6). Conclusion: RDW was significantly higher in hypertensive individuals, possibly due the presence of ongoing inflammation in hypertension. Hence RDW may be included in the routine investigations for follow up of hypertensive individuals, to identify those at risk of developing cardiovascular complications so that early intervention will be possible.

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